- A Beautiful Mind
- Brilliant mathematician and Nobel laureate John Nash (Russel Crowe) makes his seminal breakthrough while receiving his PhD at Princeton, discovering the Nash equilibrium that is now a cornerstone of economic theory. He later returns to Princeton with his wife Alicia (Jennifer Connelly) in the midst of his ordeal with schizophrenia and is instated as a professor.
- House M.D.
- House takes place at the fictional Princeton-Plainsboro Teaching Hospital.
- Exterior shots of Princeton-Plainsboro Teaching Hospital are actually Princeton's Frist Campus Center.